DI-CYN Injection

Composition: Dicyclomine Hydrochloride Injection IP 20 mg/2 ml

Class: Antispasmodic / Anticholinergic Agent

Route: IM / IV (as per approved product directions & physician advice)

Description

Dicyclomine Hydrochloride Injection is an antispasmodic medicine used to relieve smooth muscle spasms, mainly involving the gastrointestinal tract. It helps reduce abdominal cramps and colicky pain caused by intestinal muscle contractions.

Mechanism of Action (MOA)

Dicyclomine works by:

1. Blocking acetylcholine at muscarinic receptors
2. Prevents contraction of intestinal smooth muscles
3. Direct relaxation effect on GI muscles

Result:

✔ Relaxes intestinal muscles

✔ Decreases spasms

✔ Reduces abdominal cramping pain

✔ Improves functional bowel symptoms

Uses / Indications

✅ Abdominal colic

✅ Intestinal spasms

✅ Irritable Bowel Syndrome (IBS)

✅ Functional bowel disorders

✅ Spasmodic abdominal pain

Side Effects

Common:

• Dry mouth
• Dizziness
• Drowsiness
• Blurred vision
• Nausea
• Constipation
• Weakness

Less common:

• Increased heartbeat
• Difficulty urination
• Confusion (especially elderly)

Precautions

Avoid / caution in:

• Glaucoma
• Urinary retention
• Severe ulcerative colitis
• Intestinal obstruction
• Myasthenia gravis
• Elderly patients

May cause sleepiness — avoid driving/machinery if affected.